Top seed Jannik Sinner will begin his Australian Open title defence against Nicolas Jarry while women's champion Aryna Sabalenka takes on Sloane Stephens after the draw for the year's first Grand Slam was made at Melbourne Park on Thursday.
Novak Djokovic will launch his latest bid for a record-extending 11th Australian Open title and 25th Grand Slam crown against US wildcard Nishesh Basavareddy.
Second seed Iga Swiatek plays Katerina Siniakova while third seed Coco Gauff could face a tricky test against fellow American and former champion Sofia Kenin.
Olympic champion Zheng Qinwen, runner-up last year, meets a qualifier first up and is on a collision course with Sabalenka in the quarter-finals.
After adding the French Open trophy to his collection in 2024, Carlos Alcaraz kicks off his campaign to capture the one Grand Slam that has eluded him when he meets Alexander Shevchenko.
Australia's Nick Kyrgios, who has struggled with injuries since losing to Djokovic in the 2022 Wimbledon final, is due to take on Jacob Fearnley but his return to Melbourne Park remains in doubt due to an abdominal strain.
Juventus hammered Dutch side NEC Nijmegen 5-0 at home with help from two errors by goalkeeper Nikolas Polster and Olympique de Marseille of France lost 4-1 away to Besiktas as the first round of Europa League matches wrapped up on Thursday.
Jos Buttler has become the first batsman to score 15,000 career T20 runs and Liam Dawson took a three-wicket haul as a dominant England beat Sri Lanka by six wickets in Cardiff on Thursday to secure the series 2-0.
Floyd Samba wanted to give a good account of himself on his Manchester City senior debut but scoring twice and being named man of the match in Thursday's 5-0 League Cup win over Norwich City was more than the 17-year-old could have hoped for.
India opener Abhishek Sharma smashed the fastest Twenty20 International century by a batter from a full-member nation on Thursday, blasting a 30-ball hundred as the hosts thrashed Afghanistan by 127 runs in Delhi to complete a 3-0 series sweep.
Unhappy Manchester United fans have witnessed something unseen at Old Trafford in half a century on Wednesday as their side lost 3-2 at home to Brighton & Hove Albion in the third round of the League Cup after going two goals up.
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